Effective treatments for two cancers may be a step closer thanks to studies of their genetic blueprints. The results of analyses of pancreatic and brain tumours are reported in two papers published online on the 5 Sep by the journal Science. Glioblastoma multiforme, known in the UK as grade 4 astrocytoma, is the most aggressive form of brain cancer. A team at Johns Hopkins University in the US has sequenced 20,000 genes from 20 different GBM tumours. It found a mutation of a single gene – IDH1 – was most common in patients aged under 35 and in those with secondary tumours.
得益于對兩種癌癥基因藍圖的研究，人類找到有效治療方案的努力可能會更進一步。9月5日，由《科學》(Science)雜志在互聯網上發表的兩篇論文記錄了對胰腺腫瘤和腦腫瘤的分析結果。在英國被稱為四級星形細胞瘤(Astrocytoma)的多形性膠質母細胞瘤（Glioblastoma Multiforme，簡稱GBM），是一種最惡性的腦癌。美國約翰?霍普金斯大學(Johns Hopkins University)的一個小組對20個不同GBM腫瘤中的2萬個基因進行了測序。該小組發現，一種單基因突變——IDH1——在年齡在35歲以下的患者和患有轉移性腫瘤的患者中最為常見的。